MW
994.1 g/mol
Purity
>99%
Cognitive
SEMAX
Neuroprotective Cognitive Peptide
Synthetic fragment of adrenocorticotropic hormone (ACTH₄₋₁₀)
$45
Per vial · Research use only · COA available
Compound Profile
| Appearance | Lyophilized white powder |
| Molecular Weight | 994.1 g/mol |
| Amino Acids | 7 |
| Dosage | 10 mg |
| Volume | 5 mL |
| Solubility | Sterile water or saline |
| Purity | ≥98% (HPLC-UV-MS verified) |
| Storage | −20°C long-term · 4°C short-term · Protect from light |
Amino Acid Sequence
Met-Glu-His-Phe-Pro-Gly-Pro
For Research Use Only. This product is not for human consumption, clinical use, or veterinary use. Must be 21+ to purchase. Not evaluated or approved by the FDA for any therapeutic use. Introduction into humans or animals is strictly prohibited by law.
Overview
About SEMAX
Semax is a synthetic peptide derived from the adrenocorticotropic hormone (ACTH₄₋₁₀) fragment, widely studied for its roles in cognitive support, neuroprotection, neurotransmitter regulation, and stress-response modulation. Its diverse effects within the central nervous system make it a key compound of interest in neurobiology and cognitive-performance research.
Mechanism of Action
How It Works
Semax modulates BDNF and NGF expression, influences dopamine and serotonin metabolism, and protects neurons from oxidative stress and apoptotic pathways. Its activity at the melanocortin receptor system contributes to its nootropic and anti-stress properties. Research points to enhanced cerebral blood flow and gene expression changes relevant to neuroprotection following ischemic events.
Scientific Literature
Research Highlights
BDNF upregulation — supports neuronal growth, survival, and synaptic plasticity
Neuroprotection and cognitive function — studied extensively for stroke recovery
Neurotransmitter modulation — influences dopamine and serotonin pathways
Anti-inflammatory pathway regulation — reduces oxidative stress in CNS research models
Cerebral metabolic enhancement — supports glucose uptake and oxygen utilization
Stress response modulation — influences HPA axis signaling in experimental settings
Potential applications in Alzheimer's, Parkinson's, and optic nerve disease research
Research Disclaimer: All research highlights are derived from published preclinical, in vitro, and animal studies. Results observed in laboratory models may not translate to human outcomes. Genfinite makes no claims regarding therapeutic efficacy. All products are sold strictly for scientific research purposes only.
Handling
Storage & Reconstitution
Dry Storage
Store lyophilized powder at −20°C, away from light and moisture. Do not open until ready to use. Shelf life is significantly extended by proper dry storage.
Reconstitution
Reconstitute using Sterile water or saline. Add solvent slowly to the side of the vial and allow to dissolve gently. Do not shake vigorously.
Post-Reconstitution
Store reconstituted solution refrigerated at 4°C. Use within your laboratory's established timeframe. Do not refreeze after reconstitution.
